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The drug name is Contrave. Using two separate drugs to lose weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the people that go through it one should err to the side of caution and let the FDA do its job and demand some investigation be done so that the public recognizes the side effects and hazards of the medications before we take them. Keep in mind that drug companies are in business to make money and that they would say everything to keep people on his or her medications. Researchers found out that participants taking this drug for any year, dropped excess weight within a month and have kept the weight off through the entire 56 weeks from the study. Contrave is often a combination from the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs that are made up of more than one active ingredient, which might make them more potent and safer. Combo-pilling could be the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular could be the fact that as of right now there are not any long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug may also raise blood pressure level and heartbeat, and mustn't be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not used in patients with uncontrolled high blood pressure level, and also by you are not heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking. Suboxone contains two drugs; buprenorphine and naloxone. The naloxone is irrelevant when the addict uses the medication properly, but when the tablet is dissolved in water and injected the naloxone may cause instant withdrawal. When suboxone can be used correctly, the naloxone is destroyed inside liver after that uptake in the intestines and contains no therapeutic effect. Buprenorphine will be the active substance; it can be absorbed beneath the tongue (and through the mouth) but destroyed from the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I manipulate this formulation when the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have also treated addicts who may have had gastric bypass, in which the first area of the intestine is bypassed and also the stomach contents empty into a more distal the main small intestine. In such cases the naloxone escapes ?first pass metabolism', the process with normal anatomy the location where the drug is taken up from the duodenum and transferred straight to the liver by the portal vein, where it's quickly and completely destroyed. After gastric bypass naloxone can be used up by areas of the intestine which are not served by the portal system, causing blood degrees of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.